Mats Nilsson's lab

Spatially resolved biology

Publications


A complete archive of all our publications, grouped by subject


Technology development


Pooled optical screening in bacteria using chromosomally expressed barcodes


Ruben R. G. Soares, Daniela A. García-Soriano, Jimmy Larsson, David Fange, Dvir Schirman, Marco Grillo, Anna Knöppel, Beer Chakra Sen, Fabian Svahn, Spartak Zikrin, Michael Ratz, Mats Nilsson, Johan Elf

Communications Biology, vol. 8, 2025, p. 851


Open-source, high-throughput targeted in situ transcriptomics for developmental and tissue biology


Hower Lee, Christoffer Mattsson Langseth, Sergio Marco Salas, Sanem Sariyar, Andreas Metousis, Eneritz Rueda-Alaña, Christina Bekiari, Emma Lundberg, Fernando García-Moreno, Marco Grillo, Mats Nilsson

Development, vol. 151, 2024


Spatial Multimodal Analysis of Transcriptomes and Metabolomes in Tissues


Marco Vicari, R. Mirzazadeh, A. Nilsson, Reza Shariatgorji, Patrik Bjärterot, L. Larsson, Hower Lee, M. Nilsson, Julia Foyer, Markus Ekvall, Paulo Czarnewski, Xiaoqun Zhang, P. Svenningsson, P. Andrén, J. Lundeberg

Nature Biotechnology, vol. 42, 2024, pp. 1046–1050


Direct RNA targeted in situ sequencing for transcriptomic profiling in tissue


Hower Lee, Sergio Marco Salas, Daniel Gyllborg, M. Nilsson

Scientific Reports, 2022


De novo spatiotemporal modelling of cell-type signatures in the developmental human heart using graph convolutional neural networks


Sergio Marco Salas, Xiao Yuan, Christer Sylven, M. Nilsson, C. Wählby, Gabriele Partel

PLoS Comput. Biol., 2022


PoSTcode: Probabilistic image-based spatial transcriptomics decoder


M. Gataric, Jun Sung Park, Tong Li, Vasyl Vaskivskyi, J. Svedlund, C. Strell, Kenny Roberts, M. Nilsson, L. Yates, O. Bayraktar, M. Gerstung

bioRxiv, 2021


Matisse: a MATLAB-based analysis toolbox for in situ sequencing expression maps


Sergio Marco Salas, Daniel Gyllborg, C. Langseth, M. Nilsson

BMC Bioinformatics, 2021


Automated identification of the mouse brain’s spatial compartments from in situ sequencing data


Gabriele Partel, Markus M. Hilscher, G. Milli, L. Solorzano, Anna H. Klemm, M. Nilsson, Carolina Wählby

BMC Biology, 2020


Single cell RNA expression analysis using flow cytometry based on specific probe ligation and rolling circle amplification.


Yansong Zhao, Chen Lin, Pengcheng Wu, Xiaoyuan Chen, Yuancun Zhao, Yupeng Li, Lu Chen, M. Nilsson, Rongqin Ke

ACS Sensors, 2020


Probabilistic cell typing enables fine mapping of closely related cell types in situ


Xiaoyan Qian, K. Harris, T. Hauling, Dimitris Nicoloutsopoulos, A. B. Muñoz-Manchado, N. Skene, J. Hjerling-Leffler, M. Nilsson

Nature Methods, 2019


RollFISH achieves robust quantification of single-molecule RNA biomarkers in paraffin-embedded tumor tissue samples


Chenglin Wu, Michele Simonetti, Carla Rossell, Marco Mignardi, R. Mirzazadeh, L. Annaratone, C. Marchiò, A. Sapino, M. Bienko, N. Crosetto, M. Nilsson

Communications Biology, 2018


Emerging fluorescence technology to study the spatial and temporal dynamics of organelles within cells


L. Solorzano, Maxime Bombrun, P. Ranefall, Joakim Lindblad, Amin Allalou, Gabriele, Partel, Xiaoyan Qian, M. Nilsson, Carolina Wählby, Hui Gao, N. Mejhert, Peter Arne

2017


Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ


Marco Mignardi, A. Mezger, Xiaoyan Qian, L. La Fleur, J. Botling, Chatarina Larsson, M. Nilsson

Nucleic Acids Research, 2015


Image based in situ sequencing for RNA analysis in tissue


A. Pacureanu, Rongqin Ke, Marco Mignardi, M. Nilsson, Carolina Wählby

IEEE International Symposium on Biomedical Imaging, 2014


In situ detection of individual mRNA molecules and protein complexes or post-translational modifications using padlock probes combined with the in situ proximity ligation assay


I. Weibrecht, Elin Lundin, Sara Kiflemariam, Marco Mignardi, I. Grundberg, Chatarina Larsson, B. Koos, M. Nilsson, O. Söderberg

Nature Protocols, 2013


In situ sequencing for RNA analysis in preserved tissue and cells


Rongqin Ke, Marco Mignardi, A. Pacureanu, J. Svedlund, J. Botling, Carolina Wählby, M. Nilsson

Nature Methods, 2013


Study of gene-specific DNA repair in the comet assay with padlock probes and rolling circle amplification.


S. Henriksson, S. Shaposhnikov, M. Nilsson, A. Collins

Toxicology Letters, 2011


In situ detection and genotyping of individual mRNA molecules


Chatarina Larsson, I. Grundberg, O. Söderberg, M. Nilsson

Nature Methods, 2010


Detection of Alu sequences and mtDNA in comets using padlock probes.


S. Shaposhnikov, Chatarina Larsson, S. Henriksson, A. Collins, M. Nilsson

Mutagenesis, 2006


Cancer biology


Spatial transcriptomics differences of histopathological growth patterns in colorectal cancer liver metastases


Maria Escriva Conde, Axel Andersson, Peter Vermeulen, Mats Nilsson, Hanna Nyström

British Journal of Cancer, 2026


Spatially resolved T cell receptor diversity mapping uncovers variability of the cancer immune microenvironment


Anastasia Magoulopoulou, Maria Chatzinikolaou, Andreas Metousis, Taobo Hu, Hui Yu, Ioannis Zerdes, Kang Wang, Theodoros Foukakis, Mengping Long, Karin Leandersson, Patrick Micke, Carina Strell, Mats Nilsson

eBioMedicine, vol. 127, 2026, p. 106264


Cell atlas of the developing human meninges reveals a dura-like nature of meningiomas


Elin Vinsland, Sergio Marco Salas, Ivana Kapustová, Lijuan Hu, Simone Webb, Xiaofei Li, Xiaoling He, Mats Nilsson, Muzlifah Haniffa, Roger A. Barker, Oscar Persson, David R. Raleigh, Erik Sundström, Peter Lönnerberg, Sten Linnarsson

Nature Cell Biology, 2026


Charting the single-cell and spatial landscape of IDH-wild-type glioblastoma with GBmap


Cristian Ruiz-Moreno, Sergio Marco Salas, Erik Samuelsson, Mariia Minaeva, Ignacio Ibarra, Marco Grillo, Sebastian Brandner, Ananya Roy, Karin Forsberg-Nilsson, Mariette E. G. Kranendonk, Fabian J. Theis, Mats Nilsson, Hendrik G. Stunnenberg

Neuro-Oncology, vol. 27, 2025, pp. 2281--2295


Spatial transcriptome mapping of the desmoplastic growth pattern of colorectal liver metastases by in situ sequencing reveals a biologically relevant zonation of the Desmoplastic Rim


Axel Andersson, Maria Escriva Conde, Olga Surova, Peter Vermeulen, Carolina Wählby, Mats Nilsson, Hanna Nyström

Clinical Cancer Research, vol. 30, 2024 Jul, pp. 4517–4529


Spatial genomics maps the structure, nature and evolution of cancer clones


A. Lomakin, J. Svedlund, C. Strell, M. Gataric, Artem Shmatko, Gleb D. Rukhovich, Jun Sung Park, Y. Ju, S. Dentro, Vitalii Kleshchevnikov, Vasyl Vaskivskyi, Tong Li, O. Bayraktar, Sarah Pinder, A. Richardson, S. Santagata, P. Campbell, H. Russnes, M. Gerstung, M. Nilsson, L. Yates

Nature, 2022


Harmonized single-cell landscape, intercellular crosstalk and tumor architecture of glioblastoma


C. Ruiz-Moreno, Sergio Marco Salas, Erik R Samuelsson, S. Brandner, M. Kranendonk, M. Nilsson, H. Stunnenberg

bioRxiv, 2022


EPCO-21. THE SPATIAL ORGANIZATION OF H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA


Ilon Liu, Jiang Li, Erik R Samuelsson, Sergio Marco Salas, A. Beck, Olivia A Hack, Daeun Jeong, McKenzie L Shaw, B. Englinger, Jenna LaBelle, Hafsa M Mire, S. Madlener, Lisa Mayr, Michael A Quezada, Maria C Trissal, E. Panditharatna, K. Ernst, Taylor A. Gatesman, Matthew J Halbert, Hana Pálová, P. Pokorná, J. Štěrba, O. Slabý, R. Geyeregger, A. Diaz, A. Resnick, M. Suvà, David Jones, S. Agnihotri, Jessica Ostlin, C. Koschmann, C. Haberler, T. Czech, I. Slavc, J. Cotter, K. Ligon, S. Alexandrescu, W. Yung, I. Arrillaga-Romany, J. Gojo, M. Monje, M. Nilsson, Mariella G. Filbin

Neuro-Oncology, 2022


The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location


Ilon Liu, Li Jiang, Erik R Samuelsson, Sergio Marco Salas, A. Beck, Olivia A Hack, Daeun Jeong, McKenzie L Shaw, B. Englinger, Jenna LaBelle, Hafsa M Mire, S. Madlener, Lisa Mayr, Michael A Quezada, Maria C Trissal, E. Panditharatna, K. Ernst, Jayne Vogelzang, Taylor A. Gatesman, Matthew E. Halbert, Hana Pálová, P. Pokorná, J. Štěrba, O. Slabý, R. Geyeregger, A. Diaz, Izac J. Findlay, M. Dun, A. Resnick, M. Suvà, David C. Jones, S. Agnihotri, J. Svedlund, C. Koschmann, C. Haberler, T. Czech, I. Slavc, J. Cotter, K. Ligon, S. Alexandrescu, W. Yung, I. Arrillaga-Romany, J. Gojo, M. Monje, M. Nilsson, Mariella G. Filbin

Nature Genetics, 2022


In situ sequencing identifies TMPRSS2–ERG fusion transcripts, somatic point mutations and gene expression levels in prostate cancers


Sara Kiflemariam, Marco Mignardi, Muhammad Akhtar Ali, A. Bergh, M. Nilsson, T. Sjöblom

Journal of Pathology, 2014


Regeneration-associated WNT signaling is activated in long-term reconstituting AC133bright acute myeloid leukemia cells.


A. Beghini, F. Corlazzoli, L. Del Giacco, M. Ré, F. Lazzaroni, Matteo Brioschi, G. Valentini, F. Ferrazzi, A. Ghilardi, M. Righi, M. Turrini, Marco Mignardi, C. Cesana, V. Bronte, M. Nilsson, E. Morra, R. Cairoli

Neoplasia, 2012


Developmental biology


Spatiotemporal gene expression and cellular dynamics of the developing human heart


Enikő Lázár, Raphaël Mauron, Žaneta Andrusivová, Julia Foyer, Mengxiao He, Ludvig Larsson, Nick Shakari, Sergio Marco Salas, Christophe Avenel, Sanem Sariyar, Jan Niklas Hansen, Marco Vicari, Paulo Czarnewski, Emelie Braun, Xiaofei Li, Olaf Bergmann, Christer Sylvén, Emma Lundberg, Sten Linnarsson, Mats Nilsson, Erik Sundström, Igor Adameyko, Joakim Lundeberg

Nature Genetics, vol. 57, 2025, pp. 2756--2771


Evolutionary convergence of sensory circuits in the pallium of amniotes


Eneritz Rueda-Alaña, Rodrigo Senovilla-Ganzo, Marco Grillo, Enrique Vázquez, Sergio Marco-Salas, Tatiana Gallego-Flores, Aitor Ordeñana-Manso, Artemis Ftara, Laura Escobar, Alberto Benguría, Ana Quintas, Ana Dopazo, Miriam Rábano, María dM Vivanco, Ana María Aransay, Daniel Garrigos, Ángel Toval, José Luis Ferrán, Mats Nilsson, Juan Manuel Encinas-Pérez, Maurizio De Pittà, Fernando García-Moreno

Science, vol. 387, 2025, eadp3411


BirthSeq, a new method to isolate and analyze dated cells in different vertebrates


Eneritz Rueda-Alaña, Marco Grillo, Enrique Vázquez, Sergio Marco Salas, Rodrigo Senovilla-Ganzo, Laura Escobar, Ana Quintas, Alberto Benguría, Ana María Aransay, Nora Bengoa-Vergniory, Ana Dopazo, Juan Manuel Encinas, Mats Nilsson, Fernando García-Moreno

Development, vol. 151, 2024


High-parametric protein maps reveal the spatial organization in early-developing human lung


Sanem Sariyar, Alexandros Sountoulidis, Jan Niklas Hansen, Sergio Marco Salas, Mariya Mardamshina, Anna Martinez Casals, Frederic Ballllosera Navarro, Zaneta Andrusivova, Xiaofei Li, Paulo Czarnewski, Joakim Lundeberg, Sten Linnarsson, Mats Nilsson, Erik Sundström, Christos Samakovlis, Emma Lundberg, Burcu Ayoglu

Nature Communications, vol. 15, 2024, p. 9381


Developmental origins of cell heterogeneity in the human lung


A. Sountoulidis, Sergio Marco Salas, Emelie Braun, Christophe Avenel, J. Bergenstråhle, Marco Vicari, Paulo Czarnewski, Jonas Theelke, A. Liontos, X. Abalo, Žaneta Andrusivová, Michaela Asp, Xiaofei Li, L. Hu, Sanem Sariyar, Anna Martinez Casals, B. Ayoglu, A. Firsova, J. Michaëlsson, E. Lundberg, C. Wählby, E. Sundström, S. Linnarsson, J. Lundeberg, M. Nilsson, C. Samakovlis

bioRxiv, 2022


Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis.


David van Bruggen, Fabio Pohl, C. Langseth, Petra Kukanja, Hower Lee, Alejandro Mossi Albiach, Mukund Kabbe, M. Meijer, S. Linnarsson, Markus M. Hilscher, M. Nilsson, E. Sundström, G. Castelo-Branco

Developmental Cell, 2022


Profiling spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin


Xiaofei Li, Žaneta Andrusivová, Paulo Czarnewski, C. Langseth, Alma Andersson, Y. Liu, Daniel Gyllborg, Emelie Braun, L. Larsson, Lijuan Hu, Zhanna Alekseenko, Hower Lee, Christophe Avenel, H. Kallner, E. Åkesson, I. Adameyko, M. Nilsson, S. Linnarsson, J. Lundeberg, E. Sundström

bioRxiv, 2022


Developmental landscape of human forebrain at a single-cell level unveils early waves of oligodendrogenesis


David van Bruggen, Fabio Pohl, C. Langseth, Petra Kukanja, Hower Lee, Mukund Kabbe, M. Meijer, Markus M. Hilscher, M. Nilsson, E. Sundström, G. Castelo-Branco

bioRxiv, 2021


De novo spatiotemporal modelling of cell-type signatures identifies novel cell populations in the developmental human heart


Sergio Marco Salas, Xiao-ying Yuan, C. Sylvén, M. Nilsson, Carolina Wählby, Gabriele Partel

bioRxiv, 2021


Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development


Katarina Tiklova, Åsa K. Björklund, L. Lahti, A. Fiorenzano, Sara Nolbrant, L. Gillberg, N. Volakakis, C. Yokota, Markus M. Hilscher, T. Hauling, Fredrik Holmström, E. Joodmardi, M. Nilsson, M. Parmar, T. Perlmann

Nature Communications, 2019


A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart


Michaela Asp, S. Giacomello, L. Larsson, Chenglin Wu, Daniel Fürth, Xiaoyan Qian, E. Wärdell, Joaquín Custodio, Johan Reimegård, Fredrik Salmén, C. Österholm, Patrik L. Ståhl, E. Sundström, E. Åkesson, O. Bergmann, M. Bienko, A. Månsson-Broberg, M. Nilsson, C. Sylvén, J. Lundeberg

Cell, 2019


Spatiotemporal structure of cell fate decisions in murine neural crest


R. Soldatov, M. Kaucká, M. Kastriti, Julian Petersen, T. Chontorotzea, Lukas Englmaier, N. Akkuratova, Yunshi Yang, M. Häring, V. Dyachuk, C. Bock, M. Farlik, Michael L. Piacentino, F. Boismoreau, Markus M. Hilscher, C. Yokota, Xiaoyan Qian, M. Nilsson, M. Bronner, L. Croci, W. Hsiao, D. Guertin, J. Brunet, G. Consalez, P. Ernfors, K. Fried, P. Kharchenko, I. Adameyko

Science, 2019


Alternative Splicing of the Chromodomain Protein Morf4l1 Pre-mRNA Has Implications on Cell Differentiation in the Developing Chicken Retina


H. Boije, H. Ring, S. Shirazi Fard, I. Grundberg, M. Nilsson, F. Hallböök

Journal of Molecular Neuroscience, 2013


Neurobiology


Oligodendroglia vulnerability in the human dorsal striatum in Parkinson's disease


Juan M. Barba-Reyes, Lisbeth Harder, Sergio Marco Salas, Methasit Jaisa-aad, Clara Muñoz-Castro, Leonardo D. Garma, Nima Rafati, Mats Nilsson, Bradley T. Hyman, Alberto Serrano-Pozo, Ana B. Muñoz-Manchado

Acta Neuropathologica, vol. 149, 2025, p. 46


Interneuron diversity in the human dorsal striatum


Leonardo D. Garma, Lisbeth Harder, Juan M. Barba-Reyes, Sergio Marco Salas, Mónica Díez-Salguero, Mats Nilsson, Alberto Serrano-Pozo, Bradley T. Hyman, Ana B. Muñoz-Manchado

Nature Communications, vol. 15, 2024, p. 6164


Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes


Markus M. Hilscher, C. Langseth, Petra Kukanja, C. Yokota, M. Nilsson, G. Castelo-Branco

BMC Biology, 2022


Spatial cell type mapping of the oligodendrocyte lineage in the mouse juvenile and adult CNS with in situ sequencing


Markus M. Hilscher, C. Langseth, Petra Kukanja, C. Yokota, M. Nilsson, G. Castelo-Branco

bioRxiv, 2021


A spatial atlas of inhibitory cell types in mouse hippocampus


Xiaoyan Qian, K. Harris, T. Hauling, Dimitris Nicoloutsopoulos, A. B. Muñoz-Manchado, N. Skene, J. Hjerling-Leffler, M. Nilsson

bioRxiv, 2018


Tissue biology


Spatial single-cell atlas reveals regional variations in healthy and diseased human lung


Alexandra B. Firsova, Sergio Marco Salas, Louis B. Kuemmerle, Xesús M. Abalo, Alexandros Sountoulidis, Ludvig Larsson, Krishnaa T. Mahbubani, Jonas Theelke, Zaneta Andrusivova, Leire Alonso Galicia, Andreas Liontos, Tamás Balassa, Ferenc Kovacs, Peter Horvath, Yuexin Chen, Janine Gote-Schniering, Mircea-Gabriel Stoleriu, Jürgen Behr, Kerstin B. Meyer, Wim Timens, Herbert B. Schiller, Malte D. Luecken, Fabian J. Theis, Joakim Lundeberg, Mats Nilsson, Martijn C. Nawijn, Christos Samakovlis

Nature Communications, vol. 16, 2025, p. 9745


A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung


A. Sountoulidis, Sergio Marco Salas, Emelie Braun, Christophe Avenel, J. Bergenstråhle, Jonas Theelke, Marco Vicari, Paulo Czarnewski, A. Liontos, X. Abalo, Žaneta Andrusivová, R. Mirzazadeh, Michaela Asp, Xiaofei Li, Lijuan Hu, Sanem Sariyar, Anna Martinez Casals, B. Ayoglu, A. Firsova, J. Michaëlsson, E. Lundberg, C. Wählby, E. Sundström, S. Linnarsson, J. Lundeberg, M. Nilsson, C. Samakovlis

Nature Cell Biology, 2023


Spatial Resolution of Mycobacterium tuberculosis Bacteria and Their Surrounding Immune Environments Based on Selected Key Transcripts in Mouse Lungs


Anastasia Magoulopoulou, Xiaoyan Qian, Todia Pediatama Setiabudiawan, Sergio Marco Salas, C. Yokota, M. Rottenberg, M. Nilsson, B. Carow

Frontiers in Immunology, 2022


Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma


B. Carow, T. Hauling, Xiaoyan Qian, I. Kramnik, M. Nilsson, M. Rottenberg

bioRxiv, 2019


Non-Random mtDNA Segregation Patterns Indicate a Metastable Heteroplasmic Segregation Unit in m.3243A>G Cybrid Cells


A. Raap, Roshan S Jahangir Tafrechi, F. M. van de Rijke, A. Pyle, Carolina Wählby, K. Szuhai, R. Ravelli, R. de Coo, H. Rajasimha, M. Nilsson, P. Chinnery, D. Samuels, G. Janssen

PLoS ONE, 2012


Computational tools


Identifying 3D signal overlaps in spatial transcriptomics data with ovrlpy


Sebastian Tiesmeyer, Niklas Müller-Bötticher, Alexander Malt, Leyao Ma, Sergio Marco-Salas, Paul Kiessling, Paul Horn, Adrien Guillot, Louis B. Kuemmerle, Frank Tacke, Fabian J. Theis, Christoph Kuppe, Mats Nilsson, Roland Eils, Brian Long, Naveed Ishaque

Nature Biotechnology, 2026


Comparing Xenium 5K and Visium HD data from identical tissue slide at a pathological perspective


Mengping Long, Taobo Hu, Weixin Wang, Junshun Gao, Nan Wang, Mats Nilsson

Journal of Experimental and Clinical Cancer Research, vol. 44, 2025, p. 219


Optimizing Xenium in situ data utility by Quality Assessment and best-practice analysis workflows


Sergio Marco Salas, Louis B. Kuemmerle, Christoffer Mattsson-Langseth, Sebastian Tismeyer, Christophe Avenel, Taobo Hu, Habib Rehman, Marco Grillo, Paulo Czarnewski, Saga Helgadottir, et al.

Nature Methods, 2025 Mar


Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images


Erik L. G. Wernersson, Eleni Gelali, Gabriele Girelli, Su Wang, David Castillo, C. Langseth, Huy Nguyen, Shyamtanu Chattoraj, Anna Martinez Casals, E. Lundberg, M. Nilsson, M. Martí-Renom, Chao-ting Wu, N. Crosetto, M. Bienko

Nature Methods, vol. 21, 2024, pp. 1245–1256


Network Visualization and Analysis of Spatially Aware Gene Expression Data with InsituNet.


J. Salamon, Xiaoyan Qian, M. Nilsson, D. Lynn

Cell Systems, 2018


Molecular diagnostics


Microfluidic toolbox using padlock probes and rolling circle amplification for direct detection and genotyping of viral RNA


João C. Varela, Priscilla Gomes da Silva, Hower Lee, João R. Mesquita, Aman Russom, Ruben R. G. Soares, Mats Nilsson

RSC Advances, 2026


A systematic implementation of padlock probing-based rolling circle amplification in an integrated microfluidic device for quantitative biomolecular analyses


Catarina R. F. Caneira, Rafaela R. Rosa, Virginia Chu, Mats Nilsson, Narayanan Madaboosi, Ruben R. G. Soares, João P. Conde

Analytica Chimica Acta, vol. 1351, 2025, p. 343834


OPENchip: an on-chip in situ molecular profiling platform for gene expression analysis and oncogenic mutation detection in single circulating tumour cells.


A. C. Lee, J. Svedlund, E. Darai, Yongju Lee, Daewon Lee, Han-Byoel Lee, Sung-Min Kim, Okju Kim, H. Bae, Ahyoun Choi, Sumin Lee, Yunjin Jeong, S. Song, Yeongjae Choi, Huiran Yeom, Caleb S. Lee, W. Han, D. S. Lee, Jin-Young Jang, N. Madaboosi, M. Nilsson, Sunghoon Kwon

Lab on a Chip, 2020


A microfluidic platform towards automated multiplexed in situ sequencing


N. Maïno, T. Hauling, G. Cappi, N. Madaboosi, D. Dupouy, M. Nilsson

Scientific Reports, 2019


Title Analysis of IAV Replication and Co-infection Dynamics bya Versatile RNA Viral Genome Labeling Method


D. Dou, I. Hernández-Neuta, Hao Wang, Henrik Östbye, Xiaoyan Qian, Swantje Thiele, Patricia Resa-Infante, Nancy Mounogou Kouassi, V. Sender, K. Hentrich, P. Mellroth, B. Henriques-Normark, ulsah Gabriel, M. Nilsson, R. Daniels

2018


Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method.


D. Dou, I. Hernández-Neuta, Hao Wang, Henrik Östbye, Xiaoyan Qian, Swantje Thiele, Patricia Resa-Infante, Nancy Mounogou Kouassi, V. Sender, K. Hentrich, P. Mellroth, B. Henriques-Normark, G. Gabriel, M. Nilsson, R. Daniels

Cell Reports, 2017


In situ rolling circle amplification detection of Crimean Congo hemorrhagic fever virus (CCHFV) complementary and viral RNA.


C. Andersson, S. Henriksson, K. Magnusson, M. Nilsson, A. Mirazimi

Virology, 2012


Methods for analysis of the cancer microenvironment and their potential for disease prediction, monitoring and personalized treatments


C. Clausson, I. Grundberg, I. Weibrecht, M. Nilsson, O. Söderberg

The EPMA Journal, 2012



Reviews


Spatial miRNomics: towards the integration of microRNAs in spatial biology


Agustín Robles-Remacho, Mats Nilsson

Nature Reviews Genetics, vol. 26, 2025, pp. 291--292


Spatially resolved microRNA expression in tissues: technologies, challenges, and opportunities


Agustín Robles-Remacho, Yimin Zou, Marco Grillo, Mats Nilsson

Trends in Genetics, 2025


Padlock Probe-Based Targeted In Situ Sequencing: Overview of Methods and Applications.


Anastasia Magoulopoulou, Sergio Marco Salas, Katarína Tiklová, Erik R Samuelsson, Markus M. Hilscher, M. Nilsson

Annual review of genomics and human genetics (Print), 2023


Fourth Generation of Next‐Generation Sequencing Technologies: Promise and Consequences


Rongqin Ke, Marco Mignardi, T. Hauling, M. Nilsson

Human Mutation, 2016


Next-generation pathology--surveillance of tumor microecology.


B. Koos, M. Kamali-Moghaddam, L. David, M. Sobrinho-Simões, A. Dimberg, M. Nilsson, Carolina Wählby, O. Söderberg

Journal of Molecular Biology, 2015


Fourth-generation sequencing in the cell and the clinic


Marco Mignardi, M. Nilsson

Genome Medicine, 2014